Your Perfect Assignment is Just a Click Away

We Write Custom Academic Papers

100% Original, Plagiarism Free, Customized to your instructions!


 1. What is the central idea of this paper (or the central ideas)? 

2. A hallmark of clinical depression is atrophy of the hippocampus. What are some observable behaviors associated with depression? What role(s) does the hippocampus play normally? How do you think this lines up with the clinical presentation of depression? What does the HPA axis mean?

3. Describe the method used for inducing depression in mice. How do the authors show that the mice are actually showing signs of depression? What is the tail suspension test? In the analysis of the tail suspension test, why do they use a two-tailed test when mice only have one tail (this is sort of a dumb dad joke but really, what is a two-tailed test)? 

4. How do the authors attempt to depress other mice, without using the “standard” method of question 3? 

5. What is the difference (most relevant to what they’re studying) between using a pathogen-free mouse and a mouse that has been treated with antibiotics?

6. The authors observe no difference in the baseline corticosterone level. Why mention this? What is corticosterone known for (relevant to what they’re studying)?

7. What specific findings do you think caused the authors to consider a role for eCB metabolism in this gut-associated depression? 

8. What is mTOR and what does its phosophorylation mean (both literally, “what is phopshorylation?” and what is the expected result of mTOR phosphorylation in the hippocampus?) I should probably talk about Western blots and phosphospecific antibodies

9. What dietary or microbial interventions were able to reduce or reverse the depression-inducing effects in mice? There was a specific species of bacterium — why did they think to try adding that one (not a trick question)?

10. How do the authors explain the beneficial effect of [the bacterium from question 9] on depression and anxiety? What evidence do they present to back this claim up? Would you say it’s convincing? Why or why not? 

Order Solution Now

Our Service Charter

1. Professional & Expert Writers: Writers Hero only hires the best. Our writers are specially selected and recruited, after which they undergo further training to perfect their skills for specialization purposes. Moreover, our writers are holders of masters and Ph.D. degrees. They have impressive academic records, besides being native English speakers.

2. Top Quality Papers: Our customers are always guaranteed of papers that exceed their expectations. All our writers have +5 years of experience. This implies that all papers are written by individuals who are experts in their fields. In addition, the quality team reviews all the papers before sending them to the customers.

3. Plagiarism-Free Papers: All papers provided by Writers Hero are written from scratch. Appropriate referencing and citation of key information are followed. Plagiarism checkers are used by the Quality assurance team and our editors just to double-check that there are no instances of plagiarism.

4. Timely Delivery: Time wasted is equivalent to a failed dedication and commitment. Writers Hero is known for timely delivery of any pending customer orders. Customers are well informed of the progress of their papers to ensure they keep track of what the writer is providing before the final draft is sent for grading.

5. Affordable Prices: Our prices are fairly structured to fit in all groups. Any customer willing to place their assignments with us can do so at very affordable prices. In addition, our customers enjoy regular discounts and bonuses.

6. 24/7 Customer Support: At Writers hero, we have put in place a team of experts who answer to all customer inquiries promptly. The best part is the ever-availability of the team. Customers can make inquiries anytime.